| | 69th Annual Golden Globe Awards - Best Performance by an Actress in a Motion Picture (Comedy or Musical): Charlize Theron (nominated) |
| | 17th Annual Critics' Choice Movie Awards - Best Actress: Charlize Theron (nominated) |
| | 17th Annual Critics' Choice Movie Awards - Best Supporting Actress: Patton Oswalt (nominated) |
| | 17th Annual Critics' Choice Movie Awards - Best Original Screenplay: Diablo Cody (nominated) |
| | 2012 Writer's Guild of America Awards for Original Screenplay - Diablo Cody (nominated) |
| | 23rd Annual Palm Springs International Film Festival - Vanguard Award |
| | 23rd Annual Palm Springs International Film Festival Variety's Indie Impact Award - Charlize Theron |
| | 2011 Los Angeles Film Critics Association - Best Supporting Actor: Patton Oswalt (Runner-up) |
| | 15th Annual Hollywood Awards - Hollywood Screenwriter Awards: Diablo Cody (won) |
| | 16th Annual International Press Academy Satellite Awards - Best Actress: Charlize Theron (nominated) |
| | 2011 Detroit Film Critics Society - Best Actress: Charlize Theron (nominated) |
| | 2011 Detroit Film Critics Society - Best Supporting Actor: Patton Oswalt (nominated) |
| | 2011 Chicago Film Critics Association - Best Supporting Actor: Patton Oswalt (nominated) |
| | 2011 Chicago Comedy Awards for Best Comedy of 2011 (nominated) |
| | 2011 Chicago Comedy Awards for Best Director of a Comedy - Jason Reitman (nominated) |
| | 2011 Chicago Comedy Awards for Best Screenwriter - Diablo Cody (nominated) |
| | 2011 Chicago Comedy Awards for Best Supporting Actor in a Comedy - Patton Oswalt (nominated) |
| | 2011 Chicago Comedy Awards for Best Actress in a Comedy - Charlize Theron (nominated) |
| | 2011 Central Ohio Film Critics Association for Best Actress - Charlize Theron (nominated) |
| | 2011 Central Ohio Film Critics Association for Best Supporting Actor - Patton Oswalt (nominated) |
| | 2011 Central Ohio Film Critics Association for Best Original Screenplay - Diablo Cody (nominated) |
| | 2011 Alliance of Women Film Journalists EDA Awards for Best Woman Screenwriter - Diablo Cody (nominated) |
| | 2011 Alliance of Women Film Journalists EDA Awards for Movie You Wanted To Love But Just Couldn't |
| | Richard Roeper's Top 11 Films of 2011 |
| | Windy City Live's Paige Wiser's Top 10 list (#4) |
| | Windy City Live's David Plummer's Top 10 list (#2) |
| | ACE Eddie Awards - Best Edited Feature Film (Comedy or Musical) - Dana E. Glauberman, A.C.E (nominated) |
| | Georgia Film Critics Association - Best Picture (nominated) - Best Actress - Charlize Theron (nominated) - Best Original Screenplay - Diablo Cody (nominated) |
| | National Society of Film Critics Awards - 3rd Place: Best Supporting Actor- Patton Oswalt (won) |
| | 2011 Santa Barbara International Film Festival - Vanguard Award (won) - Variety's Indie Impact Award - Charlize Theron (won) |
| | 2011 Whistler Film Festival - Spotlight Award of Supporting Performance of the Year - Patton Oswalt (won) |
| | NY Times movie critic A.O Scott's Top 20 List |
| | LA Times movie critic Betsey Sharkey Top Ten List (#10) |
| | SF Bay Guardian movie critic Cheryl Eddy Top Ten List (#2) |
| | MSN movie critic Glenn Whipp Top Ten List (#5) |
| | Variety movie critic Joe Leydon Top Ten List (#4) |
| | The Wall Street Journal movie critic Joe Morgenstern Top Ten List |
| | The Grand Rapids Press movie critic John Serba Top Ten List (#3) |
| | SF Bay Guardian movie critic Lynn Rapaport's Top 8 List (#7) |
| | Hollywood & Fine / Huffington Post movie critic Marshall Fine Top Ten List (#10) |
| | The Hollywood Reporter movie critic Todd McCarthy's Top 30 (#12) |